Pseudo – MEBEP Bio Science https://www.mebep.com make experiment be predigest Thu, 15 Sep 2022 02:57:36 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 N1-Me-Pseudo UTP 100mM https://www.mebep.com/mrna/n1-me-pseudo-utp-100mm/ Mon, 20 Jun 2022 06:31:58 +0000 https://mebep.com/?p=1262 Description:

N1-methyl-pseudouridine (1-Methylpseudouridine), a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density.

Product Name:

N1-Me-Pseudo-UTP,100mM Solution

(N1-Me-Pseudouridine-5'-Triphosphate trisodium salt solution)

CAS No.:

1428903-59-6

Molecular Formula:

C10H14N2Na3O15P3

Molecular Weight:

564.11

Molar absorptivity:

8500 (λ=271nm)

Specification:

AppearanceClear colorless solution
Purity(by HPLC)≥99.0%
λmax272nm±2nm
Concentration100mM±3
31P NMR(D2O)To conform structure
1H NMR(D2O)To conform structure
pH(in buffer solution)7.0±0.1

Storage Recommendation:

Please store in -20°C. Always avoid freeze-thaw cycles or exposure to frequent temperature changes. These fluctuations can greatly alter product stability.

Quality Control:

1. The concentration is verified by Uv-vis spectrophotometry.

2. This lot of N1-Me-Pseudo-UTP is free of DNase and RNase contamination.

3. The purity of this preparation is determined by HPLC.

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]]> Pseudo UTP 100mM https://www.mebep.com/mrna/pseudo-utp-100mm/ Mon, 20 Jun 2022 06:23:51 +0000 https://mebep.com/?p=1259 Description

Product NamePseudo UTP 100mM
CAS Number1175-34-4 (Free acid)
Molecular Weight550.1
Molecular FormulaC9H12N2Na3O15P3
Storage Condition-20°C
SourceChemical synthesis

Specification

TestSpecification
AppearanceClear colorless solution
λmax262nm±2nm
pH(22~25°C)7.0±0.1
Bioburden≤1cfu/ml
Endotoxin<1EU/ml
Purity (HPLC)≥97%
DNase TestingNone detectable
RNase TestingNone detectable
Concentration100mM±3%
Transcription reactionSuitable

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M062003Pseudo UTP 100mMPurity (HPLC) 97%

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]]> N1-Me-Pseudouridine https://www.mebep.com/mrna/n1-me-pseudouridine/ Mon, 20 Jun 2022 06:20:42 +0000 https://mebep.com/?p=1256 Description

Product NameN1-Me-Pseudouridine
CAS Number13860-38-3
Molecular Weight258.229
Molecular FormulaC10H14N2O6
Storage Condition2-8°C seal preservation
SourceChemical synthesis

Specification

TestSpecification
AppearanceWhite to off-white powder
Clarity of SolutionColorless, transparent liquid
Identiflcation (HNMR)Conforms to the structure
Identiflcation (HPLC)The retention time of the major peak of the Sample solution corresponds to that of the Standard solution
Purity (HPLC)≥98%
Water Content≤1.00%
Solvent residual (HPLC/GC)Total: NMT 0.23%

Order

M062002N1-Me-PseudouridinePurity (HPLC) 98%

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]]> Pseudouridine https://www.mebep.com/mrna/pseudouridine/ Mon, 20 Jun 2022 06:17:17 +0000 https://mebep.com/?p=1253 Description

Product NamePseudouridine
CAS Number1445-07-4
Molecular Weight244.2
Molecular FormulaC9H12N2O6
Storage Condition2-8°C seal preservation
SourceChemical synthesis

Specification

TestSpecification
AppearanceWhite to off-white powder
Clarity of SolutionColorless, transparent liquid
Identiflcation (HNMR)Conforms to the structure
Identiflcation (HPLC)The retention time of the major peak of the Sample solution corresponds to that of the Standard solution
Purity (HPLC)≥98%
Water Content≤1.00%
Solvent residual (HPLC/GC)Total: NMT 0.23%

Order

M062001PseudouridinePurity (HPLC) 98%

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